Guest edited by Dr. Michell Levy, articles for this edition of Critical Care Clinics include: Specificity and sensitivity;  How to use biomarkers;Physiologic Parameters as biomarkers:  What can we learn from physiologic variables and variation?;Multi-marker Panels;Coagulation biomarkers;Biomarkers in neurosurgery;Biomarkers in Trauma; and Cardiac Biomarkers

By Mitchell M. Levy, MD, Rhode Island Hospital

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